Shopping Cart

Your shopping cart is currently empty

CRAC intermediate 1 (Synonyms: 5-(S)-Fluorowillardiine)

Name: CRAC intermediate 1
Brand: TargetMol
SKU: T10884
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T10884 Copy Product Info

Purity: 99.77%

😃Good

CRAC intermediate 1 is a key intermediate used in the synthesis of the CRAC ion channel series of compounds, details from patent WO 2010122089.

CRAC intermediate 1

Copy Product Info

😃Good

Catalog No. T10884

Synonyms 5-(S)-Fluorowillardiine

CRAC intermediate 1 is a key intermediate used in the synthesis of the CRAC ion channel series of compounds, details from patent WO 2010122089.

Cas No. 1249343-86-9

Pack Size	Price	USA Stock	Global Stock
10 mg	$33	In Stock	In Stock
25 mg	$62	In Stock	In Stock
50 mg	$98	In Stock	In Stock
100 mg	$148	In Stock	In Stock
200 mg	$221	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:99.77%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	CRAC intermediate 1 is a key intermediate used in the synthesis of the CRAC ion channel series of compounds, details from patent WO 2010122089.
Synonyms	5-(S)-Fluorowillardiine

Chemical Properties

Molecular Weight	223.18
Formula	C₁₀H₇F₂N₃O
Cas No.	1249343-86-9
Smiles	Fc1cccc(F)c1C(=O)Nc1cc[nH]n1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (224.03 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4807 mL	22.4034 mL	44.8069 mL	224.0344 mL
5 mM	0.8961 mL	4.4807 mL	8.9614 mL	44.8069 mL
10 mM	0.4481 mL	2.2403 mL	4.4807 mL	22.4034 mL
20 mM	0.2240 mL	1.1202 mL	2.2403 mL	11.2017 mL
50 mM	0.0896 mL	0.4481 mL	0.8961 mL	4.4807 mL
100 mM	0.0448 mL	0.2240 mL	0.4481 mL	2.2403 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc