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Delavirdine mesylate

Name: Delavirdine mesylate
Brand: TargetMol
SKU: T7212
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7212Cas No. 147221-93-0

Alias U 90152 (mesylate), Delavirdine (mesylate), BHAP-U 90152 (mesylate)

Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).

Delavirdine mesylate

🥰Excellent

Purity: 99.99%

Catalog No. T7212Alias U 90152 (mesylate), Delavirdine (mesylate), BHAP-U 90152 (mesylate)Cas No. 147221-93-0

Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$54	In Stock	In Stock
50 mg	$76	In Stock	In Stock
100 mg	$87	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$41	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.99%

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Targets&IC50	DNA polymerase δ:>550 μM (IC50), HIV-1 RT:0.26 μM (IC50), DNA polymerase α:440 μM (IC50)
In vitro	Delavirdine (mesylate) inhibits growth of clinical isolates of HIV-1 (ED50s = <0.005-0.69 μM). Delavirdine blocks replication of 25 primary HIV-1 isolates, including strains resistant to 3'-azido-2',3'-deoxythymidine (AZT) or 2',3'-dideoxyinosine, with a mean ED50 value of 0.066 μM. Delavirdine also inhibits growth of L. infantum promastigotes (IC50 = 26.1 μM)[1].
Synonyms	U 90152 (mesylate), Delavirdine (mesylate), BHAP-U 90152 (mesylate)

Chemical Properties

Molecular Weight	552.67
Formula	C₂₃H₃₂N₆O₆S₂
Cas No.	147221-93-0
Smiles	CS(O)(=O)=O.CC(C)Nc1cccnc1N1CCN(CC1)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40.3 mg/mL (72.92 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.62 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8094 mL	9.0470 mL	18.0940 mL	90.4699 mL
5 mM	0.3619 mL	1.8094 mL	3.6188 mL	18.0940 mL
10 mM	0.1809 mL	0.9047 mL	1.8094 mL	9.0470 mL
20 mM	0.0905 mL	0.4523 mL	0.9047 mL	4.5235 mL
50 mM	0.0362 mL	0.1809 mL	0.3619 mL	1.8094 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc