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Trabikibart
😃Good
Catalog No. T80959Cas No. 2643974-98-3
Alias CSL311, CSL 311
Trabikibart is a fully human βc-specific monoclonal antibody, designated CSL311, that binds with picomolar affinity to the cytokine-binding epitope of the human βc receptor. Trabikibart exhibits potent inhibitory activity against the collective biological effects of IL-3, GM-CSF, and IL-5 on eosinophil survival, positioning it as a promising biologic agent for the study of chronic inflammatory and eosinophil-associated disorders.
Trabikibart
Trabikibart
😃Good
Purity: 95%
Catalog No. T80959Alias CSL311, CSL 311Cas No. 2643974-98-3
Trabikibart is a fully human βc-specific monoclonal antibody, designated CSL311, that binds with picomolar affinity to the cytokine-binding epitope of the human βc receptor. Trabikibart exhibits potent inhibitory activity against the collective biological effects of IL-3, GM-CSF, and IL-5 on eosinophil survival, positioning it as a promising biologic agent for the study of chronic inflammatory and eosinophil-associated disorders.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $123 | - | In Stock | |
| 5 mg | $297 | - | In Stock | |
| 10 mg | $463 | - | In Stock | |
| 25 mg | $747 | - | In Stock | |
| 50 mg | $987 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:95.6% (SDS-PAGE); 99.3% (SEC-HPLC)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Target IL-3Rβ
Antibody Information
| Description | Trabikibart is a fully human βc-specific monoclonal antibody, designated CSL311, that binds with picomolar affinity to the cytokine-binding epitope of the human βc receptor. Trabikibart exhibits potent inhibitory activity against the collective biological effects of IL-3, GM-CSF, and IL-5 on eosinophil survival, positioning it as a promising biologic agent for the study of chronic inflammatory and eosinophil-associated disorders. |
| Synonyms | CSL311, CSL 311 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID |
| Cas No. | 2643974-98-3 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | IgG4SP-Kappa |
| Recommended Isotype Control |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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