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Anti-SOST Antibody (2R551) is a Rabbit antibody targeting SOST. Anti-SOST Antibody (2R551) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-SOST Antibody (2R551) is a Rabbit antibody targeting SOST. Anti-SOST Antibody (2R551) can be used in ELISA. |
Alias | VBCH, SOST1, sclerostin, DAND6, CDD |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2R551 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SOST (rhSOST; TMPY-00925; NP_079513.1; Gln 24-Tyr 213). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteeoblasts differentiated for 21 days, and was originally identified as an important regulator of bone remodeling, homeostasis, and links bone resorption and bone apposition. Recent studies have revealed that Sclerostin protein inhibits the bone growth probably by binding to the extracellular domain of the Wnt coreceptors LRP5 and LRP6 and disrupting Wnt-induced Frizzled-LRP complex formation. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human SOST protein (TMPY-00925) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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