Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2). It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].
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Description | TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2). It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1]. |
Molecular Weight | 347.29 |
Formula | C16H12F3N5O |
CAS No. | 2681302-83-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TMDJ-035 2681302-83-8 Membrane transporter/Ion channel Metabolism Calcium Channel inhibitor inhibit