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Sontuzumab

(Synonyms: huHMFG-1, huHMFG1, Epitumomab, AS-1402, AS1402) Copy Product Info
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Synonyms: huHMFG-1, huHMFG1, Epitumomab, AS-1402, AS1402

Catalog No. T78311 Copy Product Info
Purity: 95%
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Sontuzumab (AS1402) is a humanized monoclonal antibody targeting MUC1 that binds to the extracellular MUC1 peptide sequence PDTR (Kd≈1 nM) and can be used for breast cancer research.
Sontuzumab
Cas No. 372075-37-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$163-In Stock
5 mg$428-In Stock
10 mg$687-In Stock
25 mg$1,050-In Stock
50 mg$1,390-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Sontuzumab (AS1402) is a humanized monoclonal antibody targeting MUC1 that binds to the extracellular MUC1 peptide sequence PDTR (Kd≈1 nM) and can be used for breast cancer research.
In vitro
Sontuzumab (huHMFG-1; 0–25 μg/mL) induces antibody-dependent cellular cytotoxicity (ADCC) in KM22, 1590, HG15, ZR-75-1 cells, and CHO cells transfected with human MUC1 gene. Cell lines lacking human MUC1 expression exhibit insensitivity to ADCC upon Sontuzumab treatment [1] [2].
SynonymshuHMFG-1, huHMFG1, Epitumomab, AS-1402, AS1402
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetMUC1
Chemical Properties
Cas No.372075-37-1
Antibody Information
IsotypeIgG1
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Keywords

Related Tags: Sontuzumab chemical structure | Sontuzumab in vitro