Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Denileukin diftitox (DAB 389IL-2), a fusion protein toxin combining diphtheria toxin (DT) and interleukin 2 (IL-2), selectively depletes cells with the high-affinity IL-2 receptor (IL-2R), specifically CD25. By binding to these cells, it introduces diphtheria toxin to inhibit protein synthesis, leading to cell depletion [1] [2] [3].
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Description | Denileukin diftitox (DAB 389IL-2), a fusion protein toxin combining diphtheria toxin (DT) and interleukin 2 (IL-2), selectively depletes cells with the high-affinity IL-2 receptor (IL-2R), specifically CD25. By binding to these cells, it introduces diphtheria toxin to inhibit protein synthesis, leading to cell depletion [1] [2] [3]. |
Molecular Weight | N/A |
CAS No. | 173146-27-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Denileukin diftitox 173146-27-5 inhibitor inhibit