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Anti-KIR2DL1 Antibody (4W251) (Synonyms: XXbac-BPG184J6.7, XXbac-BCX195L8.1, p58.1, NKAT-1, NKAT1, NKAT, K...)

Name: Anti-KIR2DL1 Antibody (4W251)
Brand: TargetMol
SKU: TMAY-02503
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02503 Copy Product Info

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Anti-KIR2DL1 Antibody (4W251) is a Rabbit antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody (4W251) can be used in FCM.

Anti-KIR2DL1 Antibody (4W251)

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Catalog No. TMAY-02503

Synonyms XXbac-BPG184J6.7, XXbac-BCX195L8.1, p58.1, NKAT-1, NKAT1, NKAT, KIR-K64, KIR221, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1, CD158A

Anti-KIR2DL1 Antibody (4W251) is a Rabbit antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody (4W251) can be used in FCM.

Anti-KIR2DL1 Antibody
(4W251)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$269	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-KIR2DL1 Antibody (4W251) is a Rabbit antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody (4W251) can be used in FCM.
Synonyms	XXbac-BPG184J6.7, XXbac-BCX195L8.1, p58.1, NKAT-1, NKAT1, NKAT, KIR-K64, KIR221, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1, CD158A
Ig Type	Rabbit IgG
Clone	4W251
Reactivity	Human
Specificity	Human KIR2DL1
Verified Activity	Flow cytometric analysis of Human KIR2DL1(CD158a) expression on human whole blood lymphocytes. Cells were stained with purified anti-Human KIR2DL1(CD158a), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application	FCM
Recommended Dose	FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human KIR2DL1 / CD158a (rh KIR2DL1 / CD158a; TMPY-02629; NP_055033.2; Met1-His245).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Killer cell immunoglobulin-like receptor 2DL1 or KIR2DL1 is an inhibitory Natural Killer cell immunoglobulin-like receptor with two extracellular immunoglobulin domains. KIR2DL1 is a member of the Killer cell immunoglobulin-like receptor family whose members are classified by the number of the extracellular immunoglobulin domains and the length of the cytoplasm domain. KIR2DL1 is a transmembrane glycoprotein expressed by natural killer cells and subsets of T cells. KIR2DL1 down-regulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. It has been reported that the KIR2DL1 is bound to its class I MHC ligand, HLA-Cw4. The KIR2DL1-HLA-Cw4 interface exhibits charge and shape complementarity. Specificity is mediated by a pocket in KIR2DL1 that hosts the Lys80 residue of HLA-Cw4. Many residues conserved in HLA-C and KIR2DL receptors make different interactions in KIR2DL1-HLA-Cw4 and a previously reported KIR2DL2-HLA-Cw3 complex. A dimeric aggregate of KIR-HLA-C complexes was observed in one KIR2DL1-HLA-Cw4 crystal.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/PerCP/FITC/PE
Antibody Types Available	5

Antigen Details

Immunogen	Recombinant Protein: Human KIR2DL1 / CD158a Protein (TMPY-02629)
Antigen Species	Human
Biology Area	ITIM/ITAM Immunoreceptors and Related Molecules

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

NKAT 1KIR-221KIR 221

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