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Rutin

Name: Rutin
Brand: TargetMol
SKU: T0795
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0795Cas No. 153-18-4

Alias Rutoside, Quercetin 3-O-rutinoside

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

Rutin

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Purity: 97.19%

Catalog No. T0795Alias Rutoside, Quercetin 3-O-rutinosideCas No. 153-18-4

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$36	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:97.19%

Color:Yellow

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
Targets&IC50	HCT116 cells:31.25 μg/mL, SK-N-SH cells:36 ± 3.7 µM, A549 cells:> 10 μM, BChE:18.15 μg/mL, LN-229 cells:22 ± 4.8 µM, Xanthine Oxidase (XOD):60.811 ± 0.19 μmol/L, OATP2B1:2.32 μM (EC50), Neuro-2a cells:24 ± 4.3 µM, SH-SY5Y cells:> 40 µM
In vitro	The intraperitoneal injection in mice has determined the median lethal dose (LD50) of Rutin to be 650 mg/kg.
In vivo	Rutin inhibits platelet aggregation and diminishes capillary permeability, thinning the blood and enhancing circulation. Consequently, Rutin may prevent blood clot formation and is utilized in treating heart disease and stroke.
Synonyms	Rutoside, Quercetin 3-O-rutinoside

Chemical Properties

Molecular Weight	610.52
Formula	C₂₇H₃₀O₁₆
Cas No.	153-18-4
Smiles	O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC(O)=C(O)C=C3)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.82 g/cm3

Storage & Solubility Information

Storage

store at low temperature,store under nitrogen | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 235 mg/mL (384.92 mM), Sonication is recommended.

Ethanol: 2 mg/mL (3.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 12.2 mg/mL (19.98 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6379 mL	8.1897 mL	16.3795 mL	81.8974 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.3276 mL	1.6379 mL	3.2759 mL	16.3795 mL
10 mM	0.1638 mL	0.8190 mL	1.6379 mL	8.1897 mL
20 mM	0.0819 mL	0.4095 mL	0.8190 mL	4.0949 mL
50 mM	0.0328 mL	0.1638 mL	0.3276 mL	1.6379 mL
100 mM	0.0164 mL	0.0819 mL	0.1638 mL	0.8190 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Rutin

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