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Rutin

Name: Rutin
Brand: TargetMol
SKU: T0795
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0795Cas No. 153-18-4

Alias Rutoside, Quercetin 3-O-rutinoside

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

Rutin

🥰Excellent

Purity: 97.19%

Catalog No. T0795Alias Rutoside, Quercetin 3-O-rutinosideCas No. 153-18-4

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

Pack Size	Price	Availability	Quantity
500 mg	$36	In Stock

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Purity:97.19%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
Targets&IC50	A549 cells:> 10 μM, Xanthine Oxidase (XOD):60.811 ± 0.19 μmol/L, Neuro-2a cells:24 ± 4.3 µM, HCT116 cells:31.25 μg/mL, OATP2B1:2.32 μM (EC50), SK-N-SH cells:36 ± 3.7 µM, BChE:18.15 μg/mL, LN-229 cells:22 ± 4.8 µM, SH-SY5Y cells:> 40 µM
In vitro	The intraperitoneal injection in mice has determined the median lethal dose (LD50) of Rutin to be 650 mg/kg.
In vivo	Rutin inhibits platelet aggregation and diminishes capillary permeability, thinning the blood and enhancing circulation. Consequently, Rutin may prevent blood clot formation and is utilized in treating heart disease and stroke.
Synonyms	Rutoside, Quercetin 3-O-rutinoside

Chemical Properties

Molecular Weight	610.52
Formula	C₂₇H₃₀O₁₆
Cas No.	153-18-4
Smiles	O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC(O)=C(O)C=C3)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.82 g/cm3

Storage & Solubility Information

Storage

store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 235 mg/mL (384.92 mM), Sonication is recommended.

Ethanol: 2 mg/mL (3.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 12.2 mg/mL (19.98 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6379 mL	8.1897 mL	16.3795 mL	81.8974 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.3276 mL	1.6379 mL	3.2759 mL	16.3795 mL
10 mM	0.1638 mL	0.8190 mL	1.6379 mL	8.1897 mL
20 mM	0.0819 mL	0.4095 mL	0.8190 mL	4.0949 mL
50 mM	0.0328 mL	0.1638 mL	0.3276 mL	1.6379 mL
100 mM	0.0164 mL	0.0819 mL	0.1638 mL	0.8190 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Rutin

Rutin

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