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Cruzain-IN-1

Name: Cruzain-IN-1
Brand: TargetMol
SKU: T4736
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4736Cas No. 1199523-24-4

Alias ML092

Cruzain-IN-1 (ML092) is a covalent and reversible Cruzain inhibitor (IC50: 10 nM).

Cruzain-IN-1

🥰Excellent

Purity: 99.82%

Catalog No. T4736Alias ML092Cas No. 1199523-24-4

Cruzain-IN-1 (ML092) is a covalent and reversible Cruzain inhibitor (IC50: 10 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$31	In Stock	In Stock
5 mg	$73	In Stock	In Stock
10 mg	$113	In Stock	In Stock
25 mg	$221	In Stock	In Stock
50 mg	$335	In Stock	In Stock
100 mg	$472	In Stock	In Stock
200 mg	$659	-	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.82%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Cruzain-IN-1 (ML092) is a covalent and reversible Cruzain inhibitor (IC50: 10 nM).
Targets&IC50	Cruzain:10 nM
Synonyms	ML092

Chemical Properties

Molecular Weight	300.27
Formula	C₁₄H₁₀F₂N₆
Cas No.	1199523-24-4
Smiles	CCn1cnc2c(Nc3cc(F)cc(F)c3)nc(nc12)C#N
Relative Density.	1.47 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (149.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3303 mL	16.6517 mL	33.3034 mL	166.5168 mL
5 mM	0.6661 mL	3.3303 mL	6.6607 mL	33.3034 mL
10 mM	0.3330 mL	1.6652 mL	3.3303 mL	16.6517 mL
20 mM	0.1665 mL	0.8326 mL	1.6652 mL	8.3258 mL
50 mM	0.0666 mL	0.3330 mL	0.6661 mL	3.3303 mL
100 mM	0.0333 mL	0.1665 mL	0.3330 mL	1.6652 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc