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Ginkgolic acid C17:1

Name: Ginkgolic acid C17:1
Brand: TargetMol
SKU: T6S2116
Price: 92 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6S2116Cas No. 111047-30-4

1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.

Ginkgolic acid C17:1

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Purity: 99.81%

Catalog No. T6S2116Cas No. 111047-30-4

1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$92	In Stock	In Stock
5 mg	$220	In Stock	In Stock
10 mg	$325	In Stock	In Stock
25 mg	$548	In Stock	In Stock
50 mg	$788	In Stock	In Stock
100 mg	$1,080	In Stock	In Stock
500 mg	$2,180	-	In Stock
1 mL x 10 mM (in DMSO)	$259	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.81%

Appearance:solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Ginkgolic acid C17:1 AI Summary

Ginkgolic acid C17:1 exhibits a variety of bioactivities, including inhibition of bovine brain PI-PLCgamma1 with two observed IC50 values of 2220.0 nM and 74020.0 nM at different concentrations. It effectively inhibits the growth of various human cancer cell lines, such as MCF7, HCT15, HT1197, A549, and SKOV3, with IC50 values ranging from 5.06 to over 50.0 μg/mL. Additionally, it has demonstrated growth inhibition across various human tumor cell lines with GI50 values from 31,695.67 nM to 100,000.0 nM. The compound inhibits the amidolytic activity of human tissue factor/human factor 7a with an IC50 of 68,000.0 nM and shows minimal inhibition of pig pancreatic trypsin with an IC50 greater than 200,000.0 nM. It also acts as an inhibitor of electric eel acetylcholinesterase with an IC50 value of 573.0 nM. Furthermore, its log P value is 4.04, indicating its partition coefficient between octanol and water. In an agricultural context, Ginkgolic acid C17:1 deters the feeding behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs, with increased concentrations leading to greater deterrence..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.

Chemical Properties

Molecular Weight	374.56
Formula	C₂₄H₃₈O₃
Cas No.	111047-30-4
Smiles	CCCCCCCC(CCCCCCC=CC)OC(=O)c1ccccc1O
Relative Density.	0.975g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (146.84 mM), Sonication is recommended.

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.34 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6698 mL	13.3490 mL	26.6980 mL	133.4900 mL
5 mM	0.5340 mL	2.6698 mL	5.3396 mL	26.6980 mL
10 mM	0.2670 mL	1.3349 mL	2.6698 mL	13.3490 mL
20 mM	0.1335 mL	0.6674 mL	1.3349 mL	6.6745 mL
50 mM	0.0534 mL	0.2670 mL	0.5340 mL	2.6698 mL
100 mM	0.0267 mL	0.1335 mL	0.2670 mL	1.3349 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc