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Anti-IL-1R2 Antibody (2J18) (Synonyms: interleukin 1 receptor, type II)

Catalog No. TMAY-00283 Copy Product Info
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Anti-IL-1R2 Antibody (2J18) is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Antibody (2J18) can be used in ELISA.

Anti-IL-1R2 Antibody (2J18)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00283
Synonyms interleukin 1 receptor, type II

Anti-IL-1R2 Antibody (2J18) is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Antibody (2J18) can be used in ELISA.

Anti-IL-1R2 Antibody
(2J18)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-1R2 Antibody (2J18) is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Antibody (2J18) can be used in ELISA.
Synonymsinterleukin 1 receptor, type II
Ig Type
Rabbit IgG
Clone
2J18
Reactivity
Human
Specificity
Human IL1R2
No cross-reactivity in ELISA with
Human IL1F3 / IL1RA
Human IL1R1 / CD121a
Human IL1R3 / IL1RAP
Human IL1R8 / IL1RAPL1
Human IL1R9 / IL1RAPL2
Human IL18R1 / CD218a
Less than 10% cross-reactivity in ELISA with
Human IL1RL1 / IL1R4 / ST2
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IL1R2 (rh IL1R2; TMPY-01366; Met 1-Glu 343; NP_004624.1).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. The pleiotropic cytokine IL1 is produced to regulate the development and maintenance of the inflammatory responses and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors that can bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signaling, whereas the IL-1R2/CD121b has no signaling property and acts as a decoy for IL-1. IL-1R2/CD121b structurally consisting of a ligand-binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IL1R2 protein (TMPY-01366)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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