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HBV Seq2 aa:179-186
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Catalog No. T76531 Copy Product Info
Purity: 99.23%
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HBV Seq2 aa:179-186 is a novel epitope located on the hepatitis B virus surface antigen that serves as a motif for CTL response within the H-2b system following in vitro restimulation of primed T cells. HBV Seq2 aa:179-186 is used in immunological research to study antigen presentation, cytotoxic T lymphocyte activation, and epitope-specific immune recognition mechanisms in hepatitis B virus–related cellular immunity models.
Cas No. 337464-42-3
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $691 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.23%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | HBV Seq2 aa:179-186 is a novel epitope located on the hepatitis B virus surface antigen that serves as a motif for CTL response within the H-2b system following in vitro restimulation of primed T cells. HBV Seq2 aa:179-186 is used in immunological research to study antigen presentation, cytotoxic T lymphocyte activation, and epitope-specific immune recognition mechanisms in hepatitis B virus–related cellular immunity models. |
| In vivo | Method:C57BL/6 (H-2b) mice were used to analyze cytotoxic T lymphocyte (CTL) responses to endogenously synthesized or exogenously introduced HBV surface antigen (HBsAg), including recombinant vaccinia virus and soluble antigen exposure. Result:Endogenously synthesized HBsAg efficiently elicited CTL responses even in previously non-responder mice. Two peptides, HBV Seq2 aa:179-186 (FVQWFVGL) and S(208–216) (ILSPFLPLL), functioned as effective CTL motifs in the H-2b system after in vitro restimulation. Soluble HBsAg also induced CTL responses but less efficiently than recombinant vaccinia virus. |
| Molecular Weight | 995.17 |
| Formula | C52H70N10O10 |
| Cas No. | 337464-42-3 |
| Smiles | C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)[C@@H](C)C)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)N)=O)C(C)C)=O)CCC(N)=O)=O)C=3C=4C(NC3)=CC=CC4 |
| Sequence | H-Phe-Val-Gln-Trp-Phe-Val-Gly-Leu-OH |
| Sequence Short | FVQWFVGL |
| Storage | Keep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: HBV Seq2 aa:179-186 chemical structure | HBV Seq2 aa:179-186 in vivo | HBV Seq2 aa:179-186 formula | HBV Seq2 aa:179-186 molecular weight
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