Biotin-C10-NHS Ester

Name: Biotin-C10-NHS Ester
Brand: TargetMol
SKU: T17547
Rating: 4.5 (1 reviews)

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Catalog No. T17547Cas No. 887628-40-2

Biotin-C10-NHS Ester, an alkyl/ether-based linker compound, is utilized in the synthesis of PROTACs[1].

Biotin-C10-NHS Ester

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Catalog No. T17547Cas No. 887628-40-2

Biotin-C10-NHS Ester, an alkyl/ether-based linker compound, is utilized in the synthesis of PROTACs[1].

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Product Introduction

Bioactivity

Description	Biotin-C10-NHS Ester, an alkyl/ether-based linker compound, is utilized in the synthesis of PROTACs[1].
In vitro	PROTACs consist of two distinct ligands linked by a connector; one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. By exploiting the intracellular ubiquitin-proteasome system, PROTACs enable the selective degradation of target proteins[1].

Chemical Properties

Molecular Weight	524.67
Formula	C₂₅H₄₀N₄O₆S
Cas No.	887628-40-2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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