Sterculic acid

Name: Sterculic acid
Brand: TargetMol
SKU: T41253
Rating: 4.5 (1 reviews)

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Catalog No. T41253Cas No. 738-87-4

Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].

Sterculic acid

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Catalog No. T41253Cas No. 738-87-4

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,880	35 days	35 days

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Product Introduction

Bioactivity

Description	Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].
Targets&IC50	Delta9 desaturase:0.9 μM
In vitro	Sterculic acid (SA), a cyclopropene fatty acid derived from Sterculia foetida seeds, exhibits diverse biological activities, including the reduction of adrenomedullin expression (AP, RP, APS, IML, in preparation) and mediating anti-inflammatory and protective effects. It also demonstrates a potent luteolytic effect in ovines by inhibiting progesterone synthesis, leading to luteal regression [2].
In vivo	Sterculic acid is suggested as a promising intervention for metabolic syndrome (MS), as it effectively inhibits the function of stearoyl-CoA desaturase-1 (SCD1) in vivo [3].

Chemical Properties

Molecular Weight	294.47
Formula	C₁₉H₃₄O₂
Cas No.	738-87-4
Relative Density.	0.948 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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