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Anti-TLR5 Antibody (2G565) is an antibody targeting TLR5. Anti-TLR5 Antibody (2G565) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Anti-TLR5 Antibody (2G565) is an antibody targeting TLR5. Anti-TLR5 Antibody (2G565) can be used in ELISA, WB. |
Alias | Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR 5, TIL3 |
Ig Type | Rabbit IgG |
Clone | 2G565 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: THP-1 whole cell lysate, RAW264.7 whole cell lysate, U-251 whole cell lysate, K562 whole cell lysate -All lanes: TLR5 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 98 kDa -Observed band size: 98 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human TLR5 |
Antigen Species | Human |
Gene ID | 7100 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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