Shopping Cart
Remove All
Your shopping cart is currently empty
Aselizumab
🥰Excellent
Catalog No. T78301Cas No. 395639-53-9
Alias HuDreg-55, HuDreg55
Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody that targets L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils. L-selectin plays a crucial role in directing cell migration through chemotaxis to injury sites. Aselizumab has been associated with an increased incidence of infections and leukopenia, particularly following trauma, suggesting potential safety concerns that need further investigation in clinical contexts.
Aselizumab
Aselizumab
🥰Excellent
Purity: 95%
Catalog No. T78301Alias HuDreg-55, HuDreg55Cas No. 395639-53-9
Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody that targets L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils. L-selectin plays a crucial role in directing cell migration through chemotaxis to injury sites. Aselizumab has been associated with an increased incidence of infections and leukopenia, particularly following trauma, suggesting potential safety concerns that need further investigation in clinical contexts.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $298 | - | In Stock | |
| 5 mg | $688 | - | In Stock | |
| 10 mg | $1,090 | - | In Stock | |
| 25 mg | $1,660 | - | In Stock | |
| 50 mg | $2,230 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Concentration:7.8 mg/mL
Purity:95%
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody that targets L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils. L-selectin plays a crucial role in directing cell migration through chemotaxis to injury sites. Aselizumab has been associated with an increased incidence of infections and leukopenia, particularly following trauma, suggesting potential safety concerns that need further investigation in clinical contexts. |
| In vitro | Aselizumab can form dimers through disulfide linkage with the light chains of the chimeric monoclonal HuDreg-55 [1]. At concentrations ranging from 5 to 500 ng/mL and after 25 minutes of incubation, aselizumab inhibits the L-selectin-dependent adhesion of human lymphocytes to high endothelial venules in frozen lymph node sections [3]. |
| In vivo | Aselizumab, administered intravenously at a single dose of 10 mg/kg in cynomolgus monkeys, exhibited an elimination half-life of 12.0 days [3]. |
| Synonyms | HuDreg-55, HuDreg55 |
| Cas No. | 395639-53-9 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Aselizumab | purchase Aselizumab | Aselizumab cost | order Aselizumab | Aselizumab in vivo | Aselizumab in vitro
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.