Shopping Cart
Remove All
Your shopping cart is currently empty
Aselizumab (Synonyms: HuDreg-55, HuDreg55)
Catalog No. T78301 Copy Product Info
Purity: 95%
🥰Excellent
Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody that targets L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils. L-selectin plays a crucial role in directing cell migration through chemotaxis to injury sites. Aselizumab has been associated with an increased incidence of infections and leukopenia, particularly following trauma, suggesting potential safety concerns that need further investigation in clinical contexts.
Aselizumab
Copy Product Info🥰Excellent
Catalog No. T78301
Synonyms HuDreg-55, HuDreg55
Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody that targets L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils. L-selectin plays a crucial role in directing cell migration through chemotaxis to injury sites. Aselizumab has been associated with an increased incidence of infections and leukopenia, particularly following trauma, suggesting potential safety concerns that need further investigation in clinical contexts.
Aselizumab
Cas No. 395639-53-9
Customer service consultation
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $298 | - | In Stock | |
| 5 mg | $688 | - | In Stock | |
| 10 mg | $1,090 | - | In Stock | |
| 25 mg | $1,660 | - | In Stock | |
| 50 mg | $2,230 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:95%
Appearance:Liquid
Color:Transparent
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody that targets L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils. L-selectin plays a crucial role in directing cell migration through chemotaxis to injury sites. Aselizumab has been associated with an increased incidence of infections and leukopenia, particularly following trauma, suggesting potential safety concerns that need further investigation in clinical contexts. |
| In vitro | Aselizumab can form dimers through disulfide linkage with the light chains of the chimeric monoclonal HuDreg-55 [1]. At concentrations ranging from 5 to 500 ng/mL and after 25 minutes of incubation, aselizumab inhibits the L-selectin-dependent adhesion of human lymphocytes to high endothelial venules in frozen lymph node sections [3]. |
| In vivo | Aselizumab, administered intravenously at a single dose of 10 mg/kg in cynomolgus monkeys, exhibited an elimination half-life of 12.0 days [3]. |
| Synonyms | HuDreg-55, HuDreg55 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | L-selectin |
| Molecular Weight | 144.73 kDa |
| Cas No. | 395639-53-9 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Preview
Related Tags: buy Aselizumab | purchase Aselizumab | Aselizumab cost | order Aselizumab | Aselizumab in vivo | Aselizumab in vitro | Aselizumab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.