ω-Conotoxin Bu8

Name: ω-Conotoxin Bu8
Brand: TargetMol
SKU: T80457
Rating: 4.5 (1 reviews)

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Catalog No. T80457

ω-Conotoxin Bu8 is a 25-amino-acid-residue ω-conotoxin that features three disulfide bridges. It selectively and potently inhibits rat CaV2.2-mediated depolarization-activated Ba²⁺ currents in HEK293T cells with an IC₅₀ of 89 nM [1].

ω-Conotoxin Bu8

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Catalog No. T80457

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Product Introduction

Bioactivity

Description	ω-Conotoxin Bu8 is a 25-amino-acid-residue ω-conotoxin that features three disulfide bridges. It selectively and potently inhibits rat CaV2.2-mediated depolarization-activated Ba²⁺ currents in HEK293T cells with an IC₅₀ of 89 nM [1].
Targets&IC50	Cav 2.2:89 nM

Chemical Properties

Molecular Weight	2753.13
Formula	C₁₀₃H₁₇₄N₄₂O₃₅S₆

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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