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Anti-CD59 Antibody (6C259)

😃Good
Catalog No. TMAH-00213
Alias MSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIP, MACIF, HRF-20, HRF20, G344, CD59, 1F5

Anti-CD59 Antibody (6C259) is an antibody targeting CD59. Anti-CD59 Antibody (6C259) can be used in ELISA, FC.

Anti-CD59 Antibody (6C259)

Anti-CD59 Antibody (6C259)

😃Good
Catalog No. TMAH-00213Alias MSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIP, MACIF, HRF-20, HRF20, G344, CD59, 1F5
Anti-CD59 Antibody (6C259) is an antibody targeting CD59. Anti-CD59 Antibody (6C259) can be used in ELISA, FC.
Pack SizePriceAvailabilityQuantity
50 μL198 € 7-10 days
100 μL330 € 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD59 Antibody (6C259) is an antibody targeting CD59. Anti-CD59 Antibody (6C259) can be used in ELISA, FC.
AliasMSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIP, MACIF, HRF-20, HRF20, G344, CD59, 1F5
Ig Type
Rabbit IgG
Clone
6C259
Reactivity
Human
Verified Activity
Overlay Peak curve showing Hela cells surface stained with TMAH-00213 (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Application
ELISA, FC
Recommended Dose
FC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPotent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human CD59
Antigen Species
Human
Gene ID
966
Uniprot ID
Biology Area
Cardiovascular, Immunology, Signal transduction, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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