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Anti-CD59 Antibody (6C259) is an antibody targeting CD59. Anti-CD59 Antibody (6C259) can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-CD59 Antibody (6C259) is an antibody targeting CD59. Anti-CD59 Antibody (6C259) can be used in ELISA,FCM. |
| Synonyms | MSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIP, MACIF, HRF-20, HRF20, G344, CD59, 1F5 |
| Ig Type | Rabbit IgG |
| Clone | 6C259 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing Hela cells surface stained with TMAH-00213 (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CD59 |
| Antigen Species | Human |
| Gene Name | CD59 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cardiovascular, Immunology, Signal transduction, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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