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Transthyretin-IN-2

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Catalog No. T87559Cas No. 4664-62-4

Transthyretin-IN-2 (Compound 36), a transthyretin (TTR) amyloidosis inhibitor, exhibits IC50 and pIC50 values of 1.31 μM and 5.88 μM, respectively. It is useful for researching TTR amyloidosis diseases [1].

Transthyretin-IN-2

Transthyretin-IN-2

😃Good
Catalog No. T87559Cas No. 4664-62-4
Transthyretin-IN-2 (Compound 36), a transthyretin (TTR) amyloidosis inhibitor, exhibits IC50 and pIC50 values of 1.31 μM and 5.88 μM, respectively. It is useful for researching TTR amyloidosis diseases [1].
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Transthyretin-IN-2 (Compound 36), a transthyretin (TTR) amyloidosis inhibitor, exhibits IC50 and pIC50 values of 1.31 μM and 5.88 μM, respectively. It is useful for researching TTR amyloidosis diseases [1].
Chemical Properties
Molecular Weight228.24
FormulaC14H12O3
Cas No.4664-62-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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