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Luteolin 5-O-glucoside

🥰Excellent
Catalog No. TN1896Cas No. 20344-46-1
Alias Luteollin 5-glucoside

Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.

Luteolin 5-O-glucoside

Luteolin 5-O-glucoside

🥰Excellent
Catalog No. TN1896Alias Luteollin 5-glucosideCas No. 20344-46-1
Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.
Pack SizePriceAvailabilityQuantity
1 mg$189In Stock
5 mg$479In Stock
10 mg$852In Stock
25 mg$1,180In Stock
50 mg$1,773In Stock
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Product Introduction

Bioactivity
Description
Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.
Targets&IC50
ROS:2.17 μM, NO:64.36 μM
In vitro
In RAW 264.7 murine macrophages, luteolin 5-O-glucoside showed no significant cytotoxicity at concentrations up to 200 μM. Luteolin 5-O-glucoside inhibited LPS-induced NO production with an IC₅₀ of 64.36 μM, suppressed t-BHP-induced ROS generation (IC₅₀ = 2.17 μM), and dose-dependently downregulated iNOS and COX-2 expression, indicating notable anti-inflammatory and antioxidant activity[1].
AliasLuteollin 5-glucoside
Chemical Properties
Molecular Weight448.38
FormulaC21H20O11
Cas No.20344-46-1
SmilesO(C1=C2C(OC(=CC2=O)C3=CC(O)=C(O)C=C3)=CC(O)=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.1.714g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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