Luteolin 5-O-glucoside

Name: Luteolin 5-O-glucoside
Brand: TargetMol
SKU: TN1896
Price: 189 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN1896Cas No. 20344-46-1

Alias Luteollin 5-glucoside

Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.

Luteolin 5-O-glucoside

🥰Excellent

Catalog No. TN1896Alias Luteollin 5-glucosideCas No. 20344-46-1

Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.

Pack Size	Price	Availability
1 mg	$189	In Stock
5 mg	$479	In Stock
10 mg	$852	In Stock
25 mg	$1,180	In Stock
50 mg	$1,773	In Stock

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Product Introduction

Bioactivity

Description	Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.
Targets&IC50	ROS:2.17 μM, NO:64.36 μM
In vitro	In RAW 264.7 murine macrophages, luteolin 5-O-glucoside showed no significant cytotoxicity at concentrations up to 200 μM. Luteolin 5-O-glucoside inhibited LPS-induced NO production with an IC₅₀ of 64.36 μM, suppressed t-BHP-induced ROS generation (IC₅₀ = 2.17 μM), and dose-dependently downregulated iNOS and COX-2 expression, indicating notable anti-inflammatory and antioxidant activity[1].
Alias	Luteollin 5-glucoside

Chemical Properties

Molecular Weight	448.38
Formula	C₂₁H₂₀O₁₁
Cas No.	20344-46-1
Smiles	O(C1=C2C(OC(=CC2=O)C3=CC(O)=C(O)C=C3)=CC(O)=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.714g/cm3

Storage & Solubility Information

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keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

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