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Luteolin 5-O-glucoside
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Catalog No. TN1896Cas No. 20344-46-1
Alias Luteollin 5-glucoside
Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.
Luteolin 5-O-glucoside
Copy Product Info😃Good
Catalog No. TN1896Alias Luteollin 5-glucosideCas No. 20344-46-1
Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $189 | - | In Stock | |
| 5 mg | $479 | - | In Stock | |
| 10 mg | $852 | - | In Stock | |
| 25 mg | $1,180 | - | In Stock | |
| 50 mg | $1,773 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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| Description | Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages. |
| Targets&IC50 | ROS:2.17 μM, NO:64.36 μM |
| In vitro | In RAW 264.7 murine macrophages, luteolin 5-O-glucoside showed no significant cytotoxicity at concentrations up to 200 μM. Luteolin 5-O-glucoside inhibited LPS-induced NO production with an IC₅₀ of 64.36 μM, suppressed t-BHP-induced ROS generation (IC₅₀ = 2.17 μM), and dose-dependently downregulated iNOS and COX-2 expression, indicating notable anti-inflammatory and antioxidant activity[1]. |
| Synonyms | Luteollin 5-glucoside |
| Molecular Weight | 448.38 |
| Formula | C21H20O11 |
| Cas No. | 20344-46-1 |
| Smiles | O(C1=C2C(OC(=CC2=O)C3=CC(O)=C(O)C=C3)=CC(O)=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O |
| Relative Density. | 1.714g/cm3 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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