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orcinol

Name: orcinol
Brand: TargetMol
SKU: T3748
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3748Cas No. 504-15-4

Alias 5-Methylresorcinol, 5-Methylresorcin, 5-Methyl-1,3-benzenediol, 3,5-ToluenediolOrcin, 3,5-Dihydroxytoluene

orcinol (5-Methylresorcin) is anxiolytic agent without sedative effect.

orcinol

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Purity: 99.93%

Catalog No. T3748Alias 5-Methylresorcinol, 5-Methylresorcin, 5-Methyl-1,3-benzenediol, 3,5-ToluenediolOrcin, 3,5-DihydroxytolueneCas No. 504-15-4

orcinol (5-Methylresorcin) is anxiolytic agent without sedative effect.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$31	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.93%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HPLC HNMR

Product Introduction

orcinol AI Summary

orcinol exhibits a range of biological activities, including antibacterial, antifungal, antioxidant, and phytogrowth-inhibitory effects. It inhibits Bacillus subtilis PCI219 spore germination with an IC50 of 16,800,000 nM and has noteworthy antibacterial activity against Staphylococcus epidermidis and Staphylococcus aureus with an EC50 of 4030 nM. The compound also shows phytogrowth-inhibitory activity against Amaranthus hypochondriacus and Echinochloa crusgalli, with IC50 values ranging from 1,000,000 nM to over 8,100,000 nM. In antioxidant assays, orcinol scavenges DPPH free radicals with an IC50 of 800 nM. It inhibits tyrosinase activity, with inhibition percentages ranging from 28.0% to 63.0% across different assays, indicating potential for skin whitening applications. However, it shows lower potency in inhibiting bovine brain phosphoinositide-specific phospholipase C gamma 1 (PI-PLCgamma1), with an IC50 greater than 250 µg/mL, and minimal activity against alpha-glucosidase, with an IC50 greater than 100,000 nM. The compound also demonstrates antifungal activity, with variable inhibition of Bipolaris leersiae conidial germination, reaching 80% inhibition at 500 ppm. Its antifouling activity is evident against Bugula neritina larvae, with 10% inhibition at 25 µg/mL. Physicochemical properties of orcinol include a LogP value of 1.27, a pKa of 9.3, and a consistent LogD of 1.27..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	orcinol (5-Methylresorcin) is anxiolytic agent without sedative effect.
Synonyms	5-Methylresorcinol, 5-Methylresorcin, 5-Methyl-1,3-benzenediol, 3,5-ToluenediolOrcin, 3,5-Dihydroxytoluene

Chemical Properties

Molecular Weight	124.14
Formula	C₇H₈O₂
Cas No.	504-15-4
Smiles	CC1=CC(O)=CC(O)=C1
Relative Density.	1.2900 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (362.49 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (16.11 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	8.0554 mL	40.2771 mL	80.5542 mL	402.7711 mL
5 mM	1.6111 mL	8.0554 mL	16.1108 mL	80.5542 mL
10 mM	0.8055 mL	4.0277 mL	8.0554 mL	40.2771 mL
20 mM	0.4028 mL	2.0139 mL	4.0277 mL	20.1386 mL
50 mM	0.1611 mL	0.8055 mL	1.6111 mL	8.0554 mL
100 mM	0.0806 mL	0.4028 mL	0.8055 mL	4.0277 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc