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Astragaloside II

Name: Astragaloside II
Brand: TargetMol
SKU: T3924
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3924Cas No. 84676-89-1

Alias Astrasieversianin VIII

Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, proliferation, and mineralization, through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways.

Astragaloside II

🥰Excellent

Purity: 99.7%

Catalog No. T3924Alias Astrasieversianin VIIICas No. 84676-89-1

Pack Size	Price	Availability
1 mg	$34	In Stock
5 mg	$80	In Stock
10 mg	$128	In Stock
25 mg	$215	In Stock
50 mg	$318	In Stock
100 mg	$469	In Stock
1 mL x 10 mM (in DMSO)	$133	In Stock

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Batch Information

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Purity:99.7%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, proliferation, and mineralization, through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways.
Synonyms	Astrasieversianin VIII

Chemical Properties

Molecular Weight	827.01
Formula	C₄₃H₇₀O₁₅
Cas No.	84676-89-1
Smiles	CC(=O)O[C@@H]1[C@@H](O)[C@H](O)CO[C@H]1O[C@H]1CC[C@]23C[C@]22CC[C@]4(C)[C@H]([C@@H](O)C[C@@]4(C)[C@@H]2C[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3C1(C)C)[C@@]1(C)CC[C@H](O1)C(C)(C)O
Relative Density.	1.38 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 0.1 mg/mL (insoluble)

DMSO: 100 mg/mL (120.92 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (4.84 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2092 mL	6.0459 mL	12.0918 mL	60.4588 mL
5 mM	0.2418 mL	1.2092 mL	2.4184 mL	12.0918 mL
10 mM	0.1209 mL	0.6046 mL	1.2092 mL	6.0459 mL
20 mM	0.0605 mL	0.3023 mL	0.6046 mL	3.0229 mL
50 mM	0.0242 mL	0.1209 mL	0.2418 mL	1.2092 mL
100 mM	0.0121 mL	0.0605 mL	0.1209 mL	0.6046 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc