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Anti-AACS Antibody (8J802) (Synonyms: SUR-5, ACSF1, acetoacetyl-CoA synthetase)

Catalog No. TMAY-01660 Copy Product Info
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Anti-AACS Antibody (8J802) is a Rabbit antibody targeting AACS. Anti-AACS Antibody (8J802) can be used in ELISA.

Anti-AACS Antibody (8J802)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01660
Synonyms SUR-5, ACSF1, acetoacetyl-CoA synthetase

Anti-AACS Antibody (8J802) is a Rabbit antibody targeting AACS. Anti-AACS Antibody (8J802) can be used in ELISA.

Anti-AACS Antibody
(8J802)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-AACS Antibody (8J802) is a Rabbit antibody targeting AACS. Anti-AACS Antibody (8J802) can be used in ELISA.
SynonymsSUR-5, ACSF1, acetoacetyl-CoA synthetase
Ig Type
Rabbit IgG
Clone
8J802
Reactivity
Human
Specificity
Human AACS
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Acetoacetyl-CoA Synthetase / AACS (rh Acetoacetyl-CoA Synthetase / AACS; TMPY-01427; NP_076417.2; Met1-Phe672).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAcetoacetyl-CoA Synthetase (AACS) is a novel cytosolic ketone body (acetoacetate)-specific ligase. The AACS in adipose tissue plays an important role in utilizing ketone body for the fatty acid-synthesis during adipose tissue development. It had been improved that Acetoacetyl-CoA Synthetase is an essential enzyme for the synthesis of fatty acid and cholesterol from ketone bodies, was found to be highly expressed in mouse adipose tissue, and GC box and C/EBPs motif were crucial for AACS promoter activity in 3T3-L1 adipocytes. Moreover, AACS promoter activity was controlled mainly by C/EBPalpha during adipogenesis. AACS gene expression is particularly abundant in white adipose tissue, as it is induced during adipocyte differentiation. The human AACS promoter is a PPARgamma target gene and that this nuclear receptor is recruited to the AACS promoter by direct interaction with Sp1 (stimulating protein-1). The Acetoacetyl-CoA Synthetase has important roles in the regulation of ketone body utilization in rat liver and that these hypocholesterolemic agents have the ability to remedy the impaired utilization of ketone bodies under the diabetic condition.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Acetoacetyl-CoA Synthetase / AACS Protein (TMPY-01427)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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