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3-O-Methylquercetin

🥰Excellent
Catalog No. TN1266Cas No. 1486-70-0

3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low Km value. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.

3-O-Methylquercetin
Other Forms of 3-O-Methylquercetin:
3-O-Methylquercetin tetraacetateTN29741486-69-7
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3-O-Methylquercetin

🥰Excellent
Purity: 99.87%
Catalog No. TN1266Cas No. 1486-70-0
3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low Km value. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
Pack SizePriceAvailabilityQuantity
1 mg$89In Stock
5 mg$198In Stock
10 mg$297In Stock
50 mgPreferentialIn Stock
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Purity:99.87%
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Product Introduction

Bioactivity
Description
3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low Km value. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
Targets&IC50
PDE1-PDE5:1.6-86.9 μM
Chemical Properties
Molecular Weight316.26
FormulaC16H12O7
Cas No.1486-70-0
SmilesCOc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Relative Density.1.69 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Phosphodiesterase (PDE)PDE4PDE3PDEInhibitorinhibitILReceptorIL ReceptorcAMP3-O-Methylquercetin3OMethylquercetin3 O Methylquercetin
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