Powder: -20°C for 3 years | In solvent: -80°C for 1 year
COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1]. |
In vitro | COX-2-IN-20 (Compound 5d) has potential anti-inflammatory activity against inhibition of NO in LPS-induced RAW 264.7 cell with an IC 50 of 2.87 μM [1]. |
In vivo | COX-2-IN-20 (Compound 5d) (5 mg/kg) shows better anti-inflammation and gastric protection in vivo than 10 mg/kg indomethacin [1]. |
Molecular Weight | 269.66 |
Formula | C11H9ClFN3O2 |
CAS No. | 2529451-43-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
COX-2-IN-20 2529451-43-0 inhibitor inhibit