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Anti-L1CAM Antibody (6C568)
😃Good
Catalog No. TMAY-00334
Alias SPG1, S10, NCAM-L1, N-CAM-L1, N-CAML1, MIC5, MASA, L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1
Anti-L1CAM Antibody (6C568) is a Rabbit antibody targeting L1CAM. Anti-L1CAM Antibody (6C568) can be used in ELISA(Cap).
Anti-L1CAM Antibody (6C568)
Anti-L1CAM Antibody (6C568)
😃Good
Catalog No. TMAY-00334Alias SPG1, S10, NCAM-L1, N-CAM-L1, N-CAML1, MIC5, MASA, L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1
Anti-L1CAM Antibody (6C568) is a Rabbit antibody targeting L1CAM. Anti-L1CAM Antibody (6C568) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-L1CAM Antibody (6C568) is a Rabbit antibody targeting L1CAM. Anti-L1CAM Antibody (6C568) can be used in ELISA(Cap). |
| Alias | SPG1, S10, NCAM-L1, N-CAM-L1, N-CAML1, MIC5, MASA, L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6C568 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD171 / L1CAM (rh CD171 / L1CAM; TMPY-01431; NP_000416.1; Met1-Glu1120). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling. Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuffling gait, and adducted thumbs), and spastic paraplegia syndrome. Overexpression of L1CAM in normal and cancer cells increased motility, enhanced growth rate, and promoted cell transformation and tumorigenicity. Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD171 / L1CAM Protein (TMPY-01431) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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