Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antimalarial agent 23, a benzimidazole-based compound, exhibits potent antimalarial activity, demonstrated by its low IC50 values of 0.08 μM for PfNF54 and 0.10 μM for PfK1, respectively. This compound effectively inhibits β-hematin formation, yet it does not directly interfere with the conversion of heme to hemozoin [1].
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Description | Antimalarial agent 23, a benzimidazole-based compound, exhibits potent antimalarial activity, demonstrated by its low IC50 values of 0.08 μM for PfNF54 and 0.10 μM for PfK1, respectively. This compound effectively inhibits β-hematin formation, yet it does not directly interfere with the conversion of heme to hemozoin [1]. |
Molecular Weight | 489.92 |
Formula | C24H23ClF3N5O |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antimalarial agent 23 inhibitor inhibit