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Oct3/4-inducer-1

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Catalog No. T3221Cas No. 1016535-83-3
Alias 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile

Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.

Oct3/4-inducer-1

Oct3/4-inducer-1

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Purity: 97.42%
Catalog No. T3221Alias 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrileCas No. 1016535-83-3
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30In StockIn Stock
5 mg$68In StockIn Stock
10 mg$121In StockIn Stock
25 mg$223In StockIn Stock
50 mg$323In StockIn Stock
100 mg$449In StockIn Stock
200 mg$606-In Stock
1 mL x 10 mM (in DMSO)$74In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.42%
Appearance:Solid
Color:White to Red
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Product Introduction

Oct3/4-inducer-1 AI Summary
Oct3/4-inducer-1 induces cell cycle arrest in human adult primary fibroblasts by accumulating cells at the S phase and G1 phase, with activities of 7.0% and 66.0% respectively. It also upregulates the expression of human pluripotency genes including Sox2, Oct3/4, c-Myc, Rex1, Klf4, Nanog, and Oct3/4 at varying levels. Additionally, it activates Oct3/4 in HEK293 and NCCIT cells as evidenced by increased luciferase activity..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.
Synonyms2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile
Chemical Properties
Molecular Weight241.26
FormulaC15H12FNO
Cas No.1016535-83-3
SmilesFc1ccc(COc2ccc(CC#N)cc2)cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 11 mg/mL (45.59 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.29 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1449 mL20.7245 mL41.4491 mL207.2453 mL
5 mM0.8290 mL4.1449 mL8.2898 mL41.4491 mL
10 mM0.4145 mL2.0725 mL4.1449 mL20.7245 mL
20 mM0.2072 mL1.0362 mL2.0725 mL10.3623 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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