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Anti-LILRB1/CD85j/ILT2 Antibody (1A900) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (1A900) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-LILRB1/CD85j/ILT2 Antibody (1A900) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (1A900) can be used in ELISA. |
Alias | XXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1A900 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 / LILRB1 (rh CD85 / ILT2 / ILR1 / LILRB1; TMPY-03995; ADJ55949.1; Met1-His458). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CD85 / ILT2 / ILR1 / LILRB1 Protein (TMPY-03995) |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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