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DAM-IN-1

Name: DAM-IN-1
Brand: TargetMol
SKU: T82614
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T82614 Copy Product Info

Purity: 98.33%

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DAM-IN-1 is a selective bacterial DNA Adenine Methyltransferase (Dam) inhibitor (IC50 = 48 μM). It inhibits bacterial growth (MIC = 35 μM), used for antibacterial research.

DAM-IN-1

Copy Product Info

🥰Excellent

Catalog No. T82614

DAM-IN-1 is a selective bacterial DNA Adenine Methyltransferase (Dam) inhibitor (IC50 = 48 μM). It inhibits bacterial growth (MIC = 35 μM), used for antibacterial research.

Cas No. 935279-95-1

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Pack Size	Price	USA Stock	Global Stock
5 mg	$31	-	In Stock
10 mg	$52	-	In Stock
25 mg	$106	-	In Stock
50 mg	$156	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98.33%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	DAM-IN-1 is a selective bacterial DNA Adenine Methyltransferase (Dam) inhibitor (IC50 = 48 μM). It inhibits bacterial growth (MIC = 35 μM), used for antibacterial research.
Targets&IC50	Dam:48 μM
In vitro	DAM-IN-1 inhibited T4 phage Dam methyltransferase (IC50=48 μM) and inhibited Caulobacter crescentus growth (MIC=35 μM)[1].

Chemical Properties

Molecular Weight	287.31
Formula	C₁₆H₁₇NO₄
Cas No.	935279-95-1
Smiles	O=C(O)C1=CC=C2NC(C(=O)OCC)C3CC=CC3C2=C1

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (278.44 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4806 mL	17.4028 mL	34.8056 mL	174.0281 mL
5 mM	0.6961 mL	3.4806 mL	6.9611 mL	34.8056 mL
10 mM	0.3481 mL	1.7403 mL	3.4806 mL	17.4028 mL
20 mM	0.1740 mL	0.8701 mL	1.7403 mL	8.7014 mL
50 mM	0.0696 mL	0.3481 mL	0.6961 mL	3.4806 mL
100 mM	0.0348 mL	0.1740 mL	0.3481 mL	1.7403 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc