Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Colestilan (MCI-196), a non-absorbable, non-calcium-based phosphate binder and anion exchange resin, exhibits oral activity and is utilized in the study of hypercholesterolemia [1] [2].
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Description | Colestilan (MCI-196), a non-absorbable, non-calcium-based phosphate binder and anion exchange resin, exhibits oral activity and is utilized in the study of hypercholesterolemia [1] [2]. |
In vitro | Colestilan (MCI-196) reduces cholesterol levels through bile acid adsorption within the gastrointestinal tract [2]. |
In vivo | Colestilan (MCI-196) at doses of 0.125 or 0.5 g per 15 g of feed, administered orally for 14 days, reduces serum phosphate levels and urinary phosphorus excretion in rats [3]. Additionally, it mitigates hyperphosphatemia in rats with adenine-induced renal failure over a 4-week period [1]. |
Synonyms | MCI-196, Colestimide |
Molecular Weight | N/A |
CAS No. | 95522-45-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Colestilan 95522-45-5 MCI-196 Colestimide inhibitor inhibit