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C-Laurdan

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Catalog No. T86066 Copy Product Info
Purity: 96.22%
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C-Laurdan, a fluorescent probe for imaging lipid rafts with environmentally sensitive fluorescence, exhibits strong photostability under two-photon excitation and is suitable for single and two-photon fluorescence imaging to detect lipid membrane properties such as membrane lateral organization and various membrane-associated processes. C-Laurdan is used in biophysical membrane research to study lipid raft organization, membrane fluidity, and phase behavior in cellular and model membrane systems under fluorescence microscopy platforms.
C-Laurdan
Cas No. 959839-06-6
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$187-In Stock
5 mg$465-In Stock
10 mg$673-In Stock
25 mg$987-In Stock
50 mg$1,380-In Stock
1 mL x 10 mM (in DMSO)$473-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.22%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
C-Laurdan, a fluorescent probe for imaging lipid rafts with environmentally sensitive fluorescence, exhibits strong photostability under two-photon excitation and is suitable for single and two-photon fluorescence imaging to detect lipid membrane properties such as membrane lateral organization and various membrane-associated processes. C-Laurdan is used in biophysical membrane research to study lipid raft organization, membrane fluidity, and phase behavior in cellular and model membrane systems under fluorescence microscopy platforms.
In vitro
Methods:The fluorescence spectral characteristics of C-Laurdan in environments with different polarities and lipid phases were observed, and its optical properties and application potential were analyzed.
Results:
1.The fluorescence spectrum of C-Laurdan varied with environmental polarity: a red shift occurred in polar environments, while a blue shift was observed in nonpolar environments.
2.This probe presents unique fluorescence properties in lipid phases and can be applied to the study of cell membrane phase separation [1].
Chemical Properties
Molecular Weight397.55
FormulaC25H35NO3
Cas No.959839-06-6
SmilesO=C(O)CN(C=1C=CC2=CC(=CC=C2C1)C(=O)CCCCCCCCCCC)C
Storage & Solubility Information
StorageKeep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (100.62 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5154 mL12.5770 mL25.1541 mL125.7703 mL
5 mM0.5031 mL2.5154 mL5.0308 mL25.1541 mL
10 mM0.2515 mL1.2577 mL2.5154 mL12.5770 mL
20 mM0.1258 mL0.6289 mL1.2577 mL6.2885 mL
50 mM0.0503 mL0.2515 mL0.5031 mL2.5154 mL
100 mM0.0252 mL0.1258 mL0.2515 mL1.2577 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
µL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Keywords

Related Tags: C-Laurdan chemical structure | C-Laurdan in vitro | C-Laurdan formula | C-Laurdan molecular weight