Shopping Cart

Your shopping cart is currently empty

β-Amyloid (1-15)

Name: β-Amyloid (1-15)
Brand: TargetMol
SKU: TP1229
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. TP1229Cas No. 183745-81-5

Alias Amyloid β-Protein (1-15)

β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.

β-Amyloid (1-15)

😃Good

Purity: 99.88%

Catalog No. TP1229Alias Amyloid β-Protein (1-15)Cas No. 183745-81-5

β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$40	-	In Stock
2 mg	$59	-	In Stock
5 mg	$98	-	In Stock
10 mg	$163	-	In Stock
25 mg	$276	-	In Stock
50 mg	$397	-	In Stock
100 mg	$598	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.88%

Appearance:Solid

Color:White

Resource Download

COA HPLC MS

Product Introduction

Bioactivity

Description	β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
In vitro	Produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP), β-Amyloid (1-15) appears to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition. It may have several advantages compared to measuring longer cerebrospinal fluid (CSF) Aβ species[1].
Synonyms	Amyloid β-Protein (1-15)

Chemical Properties

Molecular Weight	1826.84
Formula	C₇₈H₁₀₇N₂₅O₂₇
Cas No.	183745-81-5
Smiles	[C@H](CC1=CN=CN1)(C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CCC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CC(O)=O)=O)CO)=O)=O)=O)CCC(O)=O)=O)[C@H](C)C)=O
Relative Density.	1.59 g/cm3 (Predicted)
Sequence	Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln
Sequence Short	DAEFRHDSGYEVHHQ

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 30 mg/mL (16.42 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.5474 mL	2.7370 mL	5.4739 mL	27.3697 mL
5 mM	0.1095 mL	0.5474 mL	1.0948 mL	5.4739 mL
10 mM	0.0547 mL	0.2737 mL	0.5474 mL	2.7370 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc