keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SK-575 is a Highly Potent and Efficacious Proteolysis-Targeting Chimera Degrader of PARP1 for Treating Cancers. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations and induces potent and specific degradation of PARP1 in various human cancer cells even at low picomolar concentrations. SK-575 achieves durable tumor growth inhibition in mice when used as a single agent or in combination with cytotoxic agents, such as temozolomide and cisplatin.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 1,070.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 2,190.00 |
Description | SK-575 is a Highly Potent and Efficacious Proteolysis-Targeting Chimera Degrader of PARP1 for Treating Cancers. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations and induces potent and specific degradation of PARP1 in various human cancer cells even at low picomolar concentrations. SK-575 achieves durable tumor growth inhibition in mice when used as a single agent or in combination with cytotoxic agents, such as temozolomide and cisplatin. |
Molecular Weight | 876.97 |
Formula | C47H53FN8O8 |
CAS No. | 2523016-96-6 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SK-575 2523016-96-6 SK 575 SK575 inhibitor inhibit