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Kevetrin hydrochloride

Name: Kevetrin hydrochloride
Brand: TargetMol
SKU: T3184
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3184Cas No. 66592-89-0

Alias Thioureidobutyronitrile HCl, thioureido butyronitrile hydrochloride, 4-Isothioureidobutyronitrile hydrochloride

Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.

Kevetrin hydrochloride

🥰Excellent

Purity: 99.93%

Catalog No. T3184Alias Thioureidobutyronitrile HCl, thioureido butyronitrile hydrochloride, 4-Isothioureidobutyronitrile hydrochlorideCas No. 66592-89-0

Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.

Pack Size	Price	Availability
5 mg	$38	In Stock
10 mg	$61	In Stock
25 mg	$113	In Stock
50 mg	$182	In Stock
100 mg	$303	In Stock
1 mL x 10 mM (in DMSO)	$60	In Stock

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Batch Information

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Purity:99.93%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
Synonyms	Thioureidobutyronitrile HCl, thioureido butyronitrile hydrochloride, 4-Isothioureidobutyronitrile hydrochloride

Chemical Properties

Molecular Weight	179.67
Formula	C₅H₁₀ClN₃S
Cas No.	66592-89-0
Smiles	Cl.NC(=N)SCCCC#N
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (278.29 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5658 mL	27.8288 mL	55.6576 mL	278.2880 mL
5 mM	1.1132 mL	5.5658 mL	11.1315 mL	55.6576 mL
10 mM	0.5566 mL	2.7829 mL	5.5658 mL	27.8288 mL
20 mM	0.2783 mL	1.3914 mL	2.7829 mL	13.9144 mL
50 mM	0.1113 mL	0.5566 mL	1.1132 mL	5.5658 mL
100 mM	0.0557 mL	0.2783 mL	0.5566 mL	2.7829 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc