Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IDO1-IN-22 (Compound 3) is an inhibitor of IDO1, demonstrating potent activity with biochemical hIDO1 IC50 of 67.4 nM and HeLa hIDO1 IC50 of 17.6 nM. It exhibits excellent antitumor efficacy in an LLC xenograft model and possesses a desirable pharmacokinetic (PK) profile [1].
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Description | IDO1-IN-22 (Compound 3) is an inhibitor of IDO1, demonstrating potent activity with biochemical hIDO1 IC50 of 67.4 nM and HeLa hIDO1 IC50 of 17.6 nM. It exhibits excellent antitumor efficacy in an LLC xenograft model and possesses a desirable pharmacokinetic (PK) profile [1]. |
Molecular Weight | 387.16 |
Formula | C12H12BrFN6O3 |
CAS No. | 2126853-16-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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IDO1-IN-22 2126853-16-3 Metabolism Indoleamine 2,3-Dioxygenase (IDO) inhibitor inhibit