keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fmoc-Ala-Glu-Asn-Lys-NH2 is a peptide inhibitor that selectively targets asparagine endopeptidase (AEP) and inhibits the cleavage of amyloid precursor protein (APP). AEP, a pH-controlled cysteine proteinase, plays a crucial role in the proteolytic processing of APP, and its activity is enhanced during the aging process [1].
Description | Fmoc-Ala-Glu-Asn-Lys-NH2 is a peptide inhibitor that selectively targets asparagine endopeptidase (AEP) and inhibits the cleavage of amyloid precursor protein (APP). AEP, a pH-controlled cysteine proteinase, plays a crucial role in the proteolytic processing of APP, and its activity is enhanced during the aging process [1]. |
In vitro | Fmoc-Ala-Glu-Asn-Lys-NH2 acts as an antagonist to APP processing by AEP, unlike other small molecular inhibitors and the inactive peptide AEQK, which showed no effect[1]. |
Synonyms | Fmoc-Ala-Glu-Asn-Lys-NH2 |
Molecular Weight | 681.747 |
Formula | C33H43N7O9 |
CAS No. | 220701-06-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (146.68 mM), Sonication and heating to 80℃ are recommended.
You can also refer to dose conversion for different animals. More
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Fmoc-Ala-Glu-Asn-Lys-NH2 220701-06-4 Fmoc-Ala-Glu-Asn-Lys-NH-2 Fmoc Ala Glu Asn Lys NH2 FmocAlaGluAsnLysNH2 inhibitor inhibit