Shopping Cart
- Remove All
Your shopping cart is currently empty
SMBA1
🥰Excellent
Catalog No. T8792Cas No. 906440-37-7
SMBA1 is a highly potent Bax agonist with antitumor activity that induces cell cycle arrest and apoptosis in malignant glioma cells. SMBA1 can be used to study triple-negative breast cancer.
SMBA1
🥰Excellent
Purity: 99.2%
Catalog No. T8792Cas No. 906440-37-7
SMBA1 is a highly potent Bax agonist with antitumor activity that induces cell cycle arrest and apoptosis in malignant glioma cells. SMBA1 can be used to study triple-negative breast cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $98 | In Stock | |
| 5 mg | $238 | In Stock | |
| 10 mg | $349 | In Stock | |
| 25 mg | $568 | In Stock | |
| 50 mg | $793 | In Stock | |
| 100 mg | $1,090 | In Stock | |
| 500 mg | $2,190 | In Stock |
Add to Cart
Add to Quotation
Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
Questions
View MoreBatch Information
Select Batch
Purity:99.2%
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
| Description | SMBA1 is a highly potent Bax agonist with antitumor activity that induces cell cycle arrest and apoptosis in malignant glioma cells. SMBA1 can be used to study triple-negative breast cancer. |
| Targets&IC50 | Bax:43.3 nM (Ki) |
| In vitro | SMBA1 exhibited Bax agonist activity by inhibiting the phosphorylation of S184, promoting the insertion of Bax into the mitochondrial membrane and the formation of Bax oligomers, and thereby inducing conformational changes in Bax. SMBA1 (0, 0.1, 1, 5, 10 µM; 24 hr) potentiated Bax expression in a dose-dependent manner in A549 cells. [1] |
| In vivo | SMBA1 (2, 10, 40, 60 mg/kg; intraperitoneal injection; once daily for 10 days) exhibited antitumor activity in mice. [1] |
| Molecular Weight | 315.32 |
| Formula | C20H13NO3 |
| Cas No. | 906440-37-7 |
| Smiles | O=[N+]([O-])C1=CC2=C(C3=CC=CC=C3C2=CC4=C(O)C=CC=C4)C=C1 |
| Relative Density. | 1.392 g/cm3 (Predicted) |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy SMBA1 | purchase SMBA1 | SMBA1 cost | order SMBA1 | SMBA1 chemical structure | SMBA1 in vivo | SMBA1 in vitro | SMBA1 formula | SMBA1 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.