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Linderalactone

Name: Linderalactone
Brand: TargetMol
SKU: T5S1897
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5S1897Cas No. 728-61-0

1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.

Linderalactone

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Purity: 99.79%

Catalog No. T5S1897Cas No. 728-61-0

1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$38	-	In Stock
5 mg	$80	-	In Stock
10 mg	$128	-	In Stock
25 mg	$219	-	In Stock
50 mg	$326	-	In Stock
100 mg	$486	-	In Stock
1 mL x 10 mM (in DMSO)	$109	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.79%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.

Chemical Properties

Molecular Weight	244.29
Formula	C₁₅H₁₆O₃
Cas No.	728-61-0
Smiles	[H][C@]12OC(=O)C(CC\C=C(C)\Cc3occ(C)c13)=C2
Relative Density.	1.19g/cm3

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (225.14 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 2.5 mg/mL (10.23 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0935 mL	20.4675 mL	40.9350 mL	204.6748 mL
5 mM	0.8187 mL	4.0935 mL	8.1870 mL	40.9350 mL
10 mM	0.4093 mL	2.0467 mL	4.0935 mL	20.4675 mL
20 mM	0.2047 mL	1.0234 mL	2.0467 mL	10.2337 mL
50 mM	0.0819 mL	0.4093 mL	0.8187 mL	4.0935 mL
100 mM	0.0409 mL	0.2047 mL	0.4093 mL	2.0467 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc