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Ladanetin-6-O-β-(6′′-O-acetyl)glucoside

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Catalog No. T81956Cas No. 1256959-27-9

Ladanetin-6-O-β-(6′′-O-acetyl)glucoside, a flavonoid extracted from Dracocephalum tanguticum whole plants, exhibits antioxidant properties and cardioprotective effects, mitigating Doxorubicin-induced toxicity in H9c2 cells [1].

Ladanetin-6-O-β-(6′′-O-acetyl)glucoside

Ladanetin-6-O-β-(6′′-O-acetyl)glucoside

😃Good
Catalog No. T81956Cas No. 1256959-27-9
Ladanetin-6-O-β-(6′′-O-acetyl)glucoside, a flavonoid extracted from Dracocephalum tanguticum whole plants, exhibits antioxidant properties and cardioprotective effects, mitigating Doxorubicin-induced toxicity in H9c2 cells [1].
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Product Introduction

Bioactivity
Description
Ladanetin-6-O-β-(6′′-O-acetyl)glucoside, a flavonoid extracted from Dracocephalum tanguticum whole plants, exhibits antioxidant properties and cardioprotective effects, mitigating Doxorubicin-induced toxicity in H9c2 cells [1].
In vitro
Ladanetin-6-O-β-(6′′-O-acetyl)glucoside (compound 1) exhibits scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH), ABTS+ radicals, and ferrous ions, with an EC50 of 113 μM at concentrations ranging from 0 to 10 mM.
Chemical Properties
Molecular Weight504.44
FormulaC24H24O12
Cas No.1256959-27-9
SmilesOC1=C2C(OC(=CC2=O)C3=CC=C(O)C=C3)=CC(OC)=C1O[C@@H]4O[C@H](COC(C)=O)[C@@H](O)[C@H](O)[C@H]4O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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