store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 249.00 | |
25 mg | 8-10 weeks | $ 920.00 | |
50 mg | 8-10 weeks | $ 1,180.00 | |
100 mg | 8-10 weeks | $ 1,790.00 |
Description | TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ. |
Targets&IC50 | TBK1:22.4 nM |
In vitro | TBK1-IN-1 (1-100 μM; 72 h) inhibits the growth of A549 and LLC cells in a dose-dependent manner and suppresses the phosphorylation of downstream signaling effector protein S6K of TBK1[1]. |
Molecular Weight | 491.63 |
Formula | C27H37N7O2 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (163.40 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TBK1-IN-1 NF-Κb IκB/IKK inhibitor inhibit