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Zamerovimab
(Synonyms: SYN023, CTB011) Copy Product Info
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Synonyms: SYN023, CTB011
Catalog No. T80589 Copy Product Info
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Zamerovimab (CTB011; SYN023), a composite of human monoclonal antibodies CTB011 and CTB012, targets distinct, non-overlapping epitopes on the rabies virus (RABV) glycoprotein, with CTB011 specifically binding to antigenic site III. This compound is applicable in rabies research [1].
Zamerovimab
Cas No. 2419087-87-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $1,050 | 4-6 weeks | 4-6 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Zamerovimab (CTB011; SYN023), a composite of human monoclonal antibodies CTB011 and CTB012, targets distinct, non-overlapping epitopes on the rabies virus (RABV) glycoprotein, with CTB011 specifically binding to antigenic site III. This compound is applicable in rabies research [1]. |
| In vitro | Zamerovimab (CTB011; SYN023) at concentrations ranging from 0.001 to 100 μg/mL for 4 hours induces dose-dependent cytotoxicity in BSR cells infected with CVS, facilitating viral clearance. This cytotoxic effect is also shown to correlate with the cell specificity for expressing the G protein, which are targeted by CTB011 [1]. |
| In vivo | Zamerovimab (CTB011; SYN023), administered via intramuscular injection into the right gastrocnemius at doses ranging from 0.03 to 1.0 mg/kg for a single dose on day 35, was shown to increase the survival rate of Syrian hamsters infected with the rabies virus RABV BD06 in a dose-dependent manner. At doses of 0.03, 0.1, 0.3, and 1.0 mg/kg, the survival rates were 58%, 83%, 100%, and 100%, respectively [1]. |
| Synonyms | SYN023, CTB011 |
| Reactivity | Virus |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | RABV |
| Cas No. | 2419087-87-7 |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Zamerovimab in vivo | Zamerovimab in vitro
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