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G-5555 hydrochloride (1648863-90-4 free base)

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Catalog No. T11342
Alias G-5555 hydrochloride

G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.

G-5555 hydrochloride (1648863-90-4 free base)
Other Forms of G-5555 hydrochloride (1648863-90-4 free base):

G-5555 hydrochloride (1648863-90-4 free base)

😃Good
Catalog No. T11342Alias G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
Pack SizePriceAvailabilityQuantity
25 mgInquiry3-6 months
50 mgInquiry3-6 months
100 mgInquiry3-6 months
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
Targets&IC50
PAK2:11 nM (ki), PAK1:3.7 nM (ki)
SynonymsG-5555 hydrochloride
Chemical Properties
Molecular Weight529.42
FormulaC25H26Cl2N6O3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (188.89 mM), Sonication is recommended.
H2O: 16.67 mg/mL (31.49 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.8889 mL9.4443 mL18.8886 mL94.4430 mL
5 mM0.3778 mL1.8889 mL3.7777 mL18.8886 mL
10 mM0.1889 mL0.9444 mL1.8889 mL9.4443 mL
20 mM0.0944 mL0.4722 mL0.9444 mL4.7221 mL
DMSO
1mg5mg10mg50mg
50 mM0.0378 mL0.1889 mL0.3778 mL1.8889 mL
100 mM0.0189 mL0.0944 mL0.1889 mL0.9444 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PAK2PAK1G5555 hydrochloride (1648863904 free base)G-5555 HydrochlorideG5555 HydrochlorideG 5555 hydrochloride (1648863 90 4 free base)G 5555 Hydrochloride1648863-90-4 free base1648863-90-4
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