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Vitamin K5 hydrochloride

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Catalog No. T87621Cas No. 130-24-5

Vitamin K5 hydrochloride is a photosensitizer and antimicrobial agent that functions as a specific inhibitor of pyruvate kinase M2 (PKM2), with IC50 values of 28 μM for PKM2, 191 μM for PKM1, and 120 μM for PKL. Vitamin K5 hydrochloride induces apoptosis in colon 26 cells, supporting its application in infection and cancer research as well as its practical use as a preservative in pharmaceutical, food, and beverage formulations.

Vitamin K5 hydrochloride
Other Forms of Vitamin K5 hydrochloride:

Vitamin K5 hydrochloride

😃Good
Catalog No. T87621Cas No. 130-24-5
Vitamin K5 hydrochloride is a photosensitizer and antimicrobial agent that functions as a specific inhibitor of pyruvate kinase M2 (PKM2), with IC50 values of 28 μM for PKM2, 191 μM for PKM1, and 120 μM for PKL. Vitamin K5 hydrochloride induces apoptosis in colon 26 cells, supporting its application in infection and cancer research as well as its practical use as a preservative in pharmaceutical, food, and beverage formulations.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30-In Stock
10 mg$40-In Stock
25 mg$64-In Stock
50 mg$107-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Vitamin K5 hydrochloride is a photosensitizer and antimicrobial agent that functions as a specific inhibitor of pyruvate kinase M2 (PKM2), with IC50 values of 28 μM for PKM2, 191 μM for PKM1, and 120 μM for PKL. Vitamin K5 hydrochloride induces apoptosis in colon 26 cells, supporting its application in infection and cancer research as well as its practical use as a preservative in pharmaceutical, food, and beverage formulations.
Chemical Properties
Molecular Weight209.67
FormulaC11H12ClNO
Cas No.130-24-5
SmilesCl.OC=1C=2C=CC=CC2C(N)=CC1C
ColorOrange
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature,store under nitrogen | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (476.94 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.7694 mL23.8470 mL47.6940 mL238.4700 mL
5 mM0.9539 mL4.7694 mL9.5388 mL47.6940 mL
10 mM0.4769 mL2.3847 mL4.7694 mL23.8470 mL
20 mM0.2385 mL1.1923 mL2.3847 mL11.9235 mL
50 mM0.0954 mL0.4769 mL0.9539 mL4.7694 mL
100 mM0.0477 mL0.2385 mL0.4769 mL2.3847 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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