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IRAK inhibitor 3

Name: IRAK inhibitor 3
Brand: TargetMol
SKU: T11670
Price: 143 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11670Cas No. 1012343-93-9

IRAK inhibitor 3 is a modulator of interleukin-1 (IL-1) receptor-associated kinase (IRAK).

IRAK inhibitor 3

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Purity: 98.86%

Catalog No. T11670Cas No. 1012343-93-9

IRAK inhibitor 3 is a modulator of interleukin-1 (IL-1) receptor-associated kinase (IRAK).

Pack Size	Price	Availability
2 mg	$143	In Stock
5 mg	$239	5 days
25 mg	$658	6-8 weeks
50 mg	$855	6-8 weeks
100 mg	$1,280	6-8 weeks
1 mL x 10 mM (in DMSO)	$263	5 days

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Purity:98.86%

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COA

Product Introduction

Bioactivity

Description	IRAK inhibitor 3 is a modulator of interleukin-1 (IL-1) receptor-associated kinase (IRAK).
In vitro	IRAK inhibitor 3 can be used for treating an inflammatory condition, cell proliferative disorder, immune disorder.is an IRAK modulator.

Chemical Properties

Molecular Weight	439.49
Formula	C₂₁H₂₁N₅O₄S
Cas No.	1012343-93-9
Smiles	COc1ccc(cc1OC)-c1cnc2ccc(NCc3ccc(cc3)S(N)(=O)=O)nn12
Relative Density.	1.41 g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (22.75 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2754 mL	11.3768 mL	22.7536 mL	113.7682 mL
5 mM	0.4551 mL	2.2754 mL	4.5507 mL	22.7536 mL
10 mM	0.2275 mL	1.1377 mL	2.2754 mL	11.3768 mL
20 mM	0.1138 mL	0.5688 mL	1.1377 mL	5.6884 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc