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BMS-986122

Name: BMS-986122
Brand: TargetMol
SKU: T26869
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T26869Cas No. 313669-88-4

Alias BMS 986122

BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing μ-opioid receptors (EC50 = 3 μM).

BMS-986122

🥰Excellent

Purity: 98.42%

Catalog No. T26869Alias BMS 986122Cas No. 313669-88-4

Pack Size	Price	Availability
1 mg	$41	In Stock
5 mg	$97	In Stock
10 mg	$163	In Stock
25 mg	$328	In Stock
50 mg	$496	In Stock
100 mg	$693	In Stock
200 mg	$978	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock

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Batch Information

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Purity:98.42%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing μ-opioid receptors (EC50 = 3 μM).
Synonyms	BMS 986122

Chemical Properties

Molecular Weight	448.78
Formula	C₁₆H₁₅BrClNO₃S₂
Cas No.	313669-88-4
Smiles	COc1ccc(cc1Br)C1SCCN1S(=O)(=O)c1ccc(Cl)cc1
Relative Density.	1.586 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (222.83 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2283 mL	11.1413 mL	22.2826 mL	111.4132 mL
5 mM	0.4457 mL	2.2283 mL	4.4565 mL	22.2826 mL
10 mM	0.2228 mL	1.1141 mL	2.2283 mL	11.1413 mL
20 mM	0.1114 mL	0.5571 mL	1.1141 mL	5.5707 mL
50 mM	0.0446 mL	0.2228 mL	0.4457 mL	2.2283 mL
100 mM	0.0223 mL	0.1114 mL	0.2228 mL	1.1141 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc