Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

EGFR/ErbB-2/ErbB-4 inhibitor-2

🥰Excellent
Catalog No. T21954Cas No. 179248-61-4
Alias EGFR/ErbB2 Inhibitor

EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable compound that inhibits EGFR and c-ErbB2 with IC50 values of 20 nM and 79 nM, respectively.

EGFR/ErbB-2/ErbB-4 inhibitor-2

EGFR/ErbB-2/ErbB-4 inhibitor-2

🥰Excellent
Purity: 99.55%
Catalog No. T21954Alias EGFR/ErbB2 InhibitorCas No. 179248-61-4
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable compound that inhibits EGFR and c-ErbB2 with IC50 values of 20 nM and 79 nM, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$100In StockIn Stock
10 mg$151In StockIn Stock
25 mg$273In StockIn Stock
50 mg$411In StockIn Stock
100 mg$596In StockIn Stock
200 mg$791In StockIn Stock
1 mL x 10 mM (in DMSO)$111In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.55%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable compound that inhibits EGFR and c-ErbB2 with IC50 values of 20 nM and 79 nM, respectively.
Targets&IC50
ErbB2:0.08 μM, ERB4:1.91 μM, c-ErbB2:79 nM, EGFR:20 nM
SynonymsEGFR/ErbB2 Inhibitor
Chemical Properties
Molecular Weight387.43
FormulaC23H21N3O3
Cas No.179248-61-4
SmilesCOc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC
Relative Density.1.254 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (141.96 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 2.5 mg/mL (6.45 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5811 mL12.9056 mL25.8111 mL129.0556 mL
5 mM0.5162 mL2.5811 mL5.1622 mL25.8111 mL
10 mM0.2581 mL1.2906 mL2.5811 mL12.9056 mL
20 mM0.1291 mL0.6453 mL1.2906 mL6.4528 mL
50 mM0.0516 mL0.2581 mL0.5162 mL2.5811 mL
100 mM0.0258 mL0.1291 mL0.2581 mL1.2906 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitHN5HER1ErbB4ErbB2ErbB-1Epidermal growth factor receptorEGFR/ErbB-2/ErbB-4 inhibitor-2EGFR/ErbB2/ErbB4 inhibitor2EGFR/ErbB 2/ErbB 4 inhibitor 2EGFRc-ErbB2
Related Tags: buy EGFR/ErbB-2/ErbB-4 inhibitor-2 | purchase EGFR/ErbB-2/ErbB-4 inhibitor-2 | EGFR/ErbB-2/ErbB-4 inhibitor-2 cost | order EGFR/ErbB-2/ErbB-4 inhibitor-2 | EGFR/ErbB-2/ErbB-4 inhibitor-2 chemical structure | EGFR/ErbB-2/ErbB-4 inhibitor-2 formula | EGFR/ErbB-2/ErbB-4 inhibitor-2 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.