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MuRF1-IN-1

Name: MuRF1-IN-1
Brand: TargetMol
SKU: T12125
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T12125Cas No. 445222-91-3

MuRF1-IN-1 is an inhibitor of muscle ring finger 1.

MuRF1-IN-1

🥰Excellent

Purity: 98.88%

Catalog No. T12125Cas No. 445222-91-3

MuRF1-IN-1 is an inhibitor of muscle ring finger 1.

Pack Size	Price	Availability
1 mg	$32	In Stock
5 mg	$68	In Stock
10 mg	$111	In Stock
25 mg	$225	In Stock
50 mg	$326	In Stock
100 mg	$453	In Stock
200 mg	$613	In Stock
1 mL x 10 mM (in DMSO)	$75	In Stock

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Batch Information

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Purity:98.88%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	MuRF1-IN-1 is an inhibitor of muscle ring finger 1.
In vitro	MuRF1-IN-1 inhibited MuRF1-titin complexation with IC50 values <25 μM,

Chemical Properties

Molecular Weight	321.33
Formula	C₁₈H₁₅N₃O₃
Cas No.	445222-91-3
Smiles	CN1C(=O)C2(c3ccccc13)C(C#N)=C(N)OC1=C2C(=O)CCC1
Relative Density.	1.45 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (186.72 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1121 mL	15.5603 mL	31.1207 mL	155.6033 mL
5 mM	0.6224 mL	3.1121 mL	6.2241 mL	31.1207 mL
10 mM	0.3112 mL	1.5560 mL	3.1121 mL	15.5603 mL
20 mM	0.1556 mL	0.7780 mL	1.5560 mL	7.7802 mL
50 mM	0.0622 mL	0.3112 mL	0.6224 mL	3.1121 mL
100 mM	0.0311 mL	0.1556 mL	0.3112 mL	1.5560 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc