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Imiquimod hydrochloride
🥰Excellent
Catalog No. T22091Cas No. 99011-78-6
Alias R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl
Imiquimod hydrochloride (R 837 hydrochloride) is a selective toll-like receptor 7 (TLR7) agonist and immune response modulator with antiviral and antitumor activities. It is used in the study of external genital warts, perianal warts, cancer, COVID-19, pemphigus foliaceus, skin cancer, and psoriasis, and is commonly employed to establish psoriasis models.
Imiquimod hydrochloride
🥰Excellent
Purity: 99.98%
Catalog No. T22091Alias R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HClCas No. 99011-78-6
Imiquimod hydrochloride (R 837 hydrochloride) is a selective toll-like receptor 7 (TLR7) agonist and immune response modulator with antiviral and antitumor activities. It is used in the study of external genital warts, perianal warts, cancer, COVID-19, pemphigus foliaceus, skin cancer, and psoriasis, and is commonly employed to establish psoriasis models.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $33 | In Stock | |
| 100 mg | $45 | In Stock |
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Purity:99.98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Imiquimod hydrochloride (R 837 hydrochloride) is a selective toll-like receptor 7 (TLR7) agonist and immune response modulator with antiviral and antitumor activities. It is used in the study of external genital warts, perianal warts, cancer, COVID-19, pemphigus foliaceus, skin cancer, and psoriasis, and is commonly employed to establish psoriasis models. |
| In vivo | Imiquimod hydrochloride stimulates innate immune responses by inducing synthesis and release of cytokines, including interferon-α (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)[1]. |
| Synonyms | R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl |
| Molecular Weight | 276.77 |
| Formula | C14H17ClN4 |
| Cas No. | 99011-78-6 |
| Smiles | Cl.CC(C)Cn1cnc2c(N)nc3ccccc3c12 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Methanol: 15 mg/mL (54.20 mM), Sonication is recommended. DMSO: 5 mg/mL (18.07 mM), Sonication and heating are recommended. H2O: 2 mg/ml (7.23 mM), Sonication is recommended. Ethanol: 1 mg/mL (3.61 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
Ethanol/H2O/DMSO/Methanol
H2O/DMSO/Methanol
DMSO/Methanol
Methanol
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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